Local Infiltration Analgesia in Major Spine Surgery With Ropivacaine Versus Placebo

Hvidovre University Hospital48 enrolled

Overview

The purpose of this study is to examine whether local infiltration analgesia (LIA) with Ropivacaine and adrenaline is effective in the treatment of postoperative pain after major spine surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Pain, Postoperative

Interventions

Ropivacaine 0.5 %DRUG

Local infiltration analgesia

Isotonic NaClDRUG

Local infiltration analgesia

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients eligible for major spine surgery * must speak and understand Danish * must be able to give oral and written consent Exclusion Criteria: * alcohol or medicine abuse * treatment with opioids \> 100 mg daily * allergy to local anesthetics * severe obesity

Locations (1)

Hvidovre University Hospital

Copenhagen, Hvidovre, Denmark

Outcomes

Primary Outcomes

Postoperative Pain

Time frame: 0-48 h postoperatively

Secondary Outcomes

Analgesia consumption

Time frame: 0-48 h postoperatively

Data from ClinicalTrials.gov

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