Positive data originating from two polycystic liver patients treated with somatostatin analogues, showed a volume reduction of 38.3% and 14.9%. These two patients had complicated polycystic livers and no other therapeutic options were available. Patients who participated in LOCKCYST trial are able to benefit from active treatment. Participants will be actively treated for 24 weeks.
van Keimpema L, de Man RA, Drenth JP. Somatostatin analogues reduce liver volume in polycystic liver disease. Gut 2008 September;57(9):1338-9.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
54
lanreotide
University Hospital Gasthuisberg, University of Leuven
Leuven, Belgium
Radboud University Nijmegen Medical Center
Nijmegen, Netherlands
Liver volume reduction
Time frame: 24 weeks
Kidney volume Cyst volume
Time frame: 24 weeks
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