Radical Prostatectomy and Perioperative Fluid Therapy

Phase 4CompletedNCT00771966

Rigshospitalet, Denmark44 enrolled

Overview

The optimal amount of fluid a patient need under surgery is not clear. Both to much and to little fluid can damage the organ functions. A strategy called "Goal directed therapy", where the fluid amount a patient need is guided by the stroke volume, has shown to minimize post-operative nausea and vomiting. The investigators intend to investigate if patients treated after these standards, has a better outcome then patients treated after normal regimes, regarding post-operative orthostatic-intolerance.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Prostate Cancer

Interventions

Standard therapyPROCEDURE

Standard therapy

Maximization of cardiac stroke volume with fluid infusionPROCEDURE

Maximization of cardiac stroke volume with fluid infusion

Eligibility

Sex: MALEMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with cancer in there prostate Exclusion Criteria: * Patients who don't understand the information * ASA \> III * Patients that are under treatment with the drug triazolam * Patients with af known renal decease * Patients with a psychiatric decease * Alcohol abuse * Severe haemorrhagic decease * Cancer in the mouth,pharynx, larynx or oesophagus

Locations (1)

Dept of anesthesiology, Rigshospitalet

Copenhagen, Denmark

Outcomes

Primary Outcomes

To investigate orthostatic cardiovascular response and orthostatic intolerance in patients after removal of the prostate

Time frame: 6 hours

Secondary Outcomes

Investigate intraoperative haemodynamics

Time frame: Intraoperative

Data from ClinicalTrials.gov

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