Efficacy of Retinal Nerve Fiber Layer (RNFL) / Retinal Thickness Ratio by Cirrus OCT Utilizing Spectral -Domain Technology as a Diagnostic Predictor of Glaucoma

Yonsei University400 enrolled

Overview

Glaucoma is presumed to be an axonal disease which starts at the lamina cribrosa. This assumption has led to the monitoring of the retinal nerve fiber layer thickness for the diagnosis and monitoring of progression of glaucoma. However, varying disc size, myopia and tilted discs affect the thickness of the retinal nerve fiber layer. This study aims to ascertain the ration of the retinal nerve fiber layer against full retina as a predictor of glaucoma diagnosis and progression.

Study Type

OBSERVATIONAL

Enrollment

400

Conditions

Glaucoma Myopia

Eligibility

Sex: ALLMin age: 10 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Primary open angle glaucoma * Myopia * Myopia with evidence of glaucoma * Normal controls Exclusion Criteria: * Evidence of retinal disease * BCVA \< 0.4 * Secondary glaucoma due to intraocular inflammation * Lens induced glaucoma * Tumor induced glaucoma * Neovascular glaucoma

Locations (1)

Institute of Vision Research, Department of Ophthalmology, Severance Hospital, Yonsei University School of Medicine

Central Contacts

Chan Yun Kim, MD,PhD.

CONTACT

82-2-2228-3570 kangeye@hotmail.com

Sung Yong Kang, MD