A Phase III Trial Assessing the Pharmacodynamic Effect and the Tolerability of Grazax Treatment

Inclusion Criteria: * Positive skin prick test to Phleum pratense * Positive IgE to Phleum pratense * signed informed consent * A clinical history of moderate to severe persistent rhinoconjunctivitis symptoms Exclusion Criteria: * No uncontrolled asthma in the past 12 months * No history of an IgE mediated systemic reaction due to food, insect venom, any kind of medication or induced by exercise, where there are symptoms both from the skin and the respiratory system with or without hypotension * No history of an IgE mediated systemic reaction due to food, insect venom, any kind of medication or induced by exercise, where there are symptoms both from the skin and the respiratory system with or without hypotension