Pipeline for Uncoilable or Failed Aneurysms

Inclusion Criteria: * Age 21 to 75 years, inclusive * Patient has a single target IA in the anterior or posterior circulation that: a) Is located in the following regions of the internal carotid artery: i. Paraophthalmic (including paraclinoid, ophthalmic and hypophyseal segments) ii. Cavernous iii. Petrous b) Has a neck \>4 mm or no discernible neck AND a size (maximum fundus diameter) \>10 mm c) Has a parent vessel with diameter 2.5 - 5.0 mm distal/proximal to the target IA * Subject has provided written informed consent using the Institutional Review Board (IRB)-approved consent form * Subject has the necessary mental capacity to participate and is willing and able to comply with protocol requirements Exclusion Criteria: * More than one IA requires treatment in the next 6 months * Subarachnoid hemorrhage from target IA in the past 60 days * Unstable neurologic deficit (i.e., any worsening of clinical condition in the last 30 days) * Irreversible bleeding disorder * Platelet count \< 100 x 103 cells/mm3 or known platelet dysfunction * Inability to tolerate, documented evidence of adverse reaction or contraindication to study medications * Stent in place at the target IA * Contraindication to CT scan or MRI * Allergy to contrast used in angiography that cannot be medically controlled * Known severe allergy to platinum or cobalt/chromium alloys * Relative contraindication to angiography (e.g., serum creatinine \> 2.5 mg/dL) * Woman of child-bearing potential who cannot provide a negative pregnancy test * Evidence of active infection at the time of treatment * Other conditions of the heart, blood, brain or intracranial vessels that carry a high risk of neurologic events (e.g., severe heart failure, atrial fibrillation, known carotid stenosis) * Any comorbid disease or condition expected to compromise survival or ability to complete follow-up assessments to 180 days * Extracranial stenosis greater than 50% in the carotid artery for anterior circulation aneurysms * Intracranial stenosis greater than 50% in the treated vessel