Thrombelastogram in Patients Receiving Antiplatelet Medication Undergoing Cardiac Surgery

Sheba Medical Center60 enrolled

Overview

Study Objective is to correlate the results of preoperative platelet mapping derived from modified TEG with clinically significant postoperative bleeding and consumption of blood products.

Study Design: Prospective observational study with blinded assessment of study endpoint variables. Collection of information concerning study endpoints will be performed by the investigator blinded to the results of preoperative testing of platelet function. The information will be collected from 60 patients undergoing cardiac surgery in the Department of Cardiac Surgery of Sheba Medical Center. Study endpoints 1. Primary endpoint- resternotomy for bleeding after the surgery. 2. Secondary endpoints- chest tube output during first 24 hours after the surgery; consumption of blood products during first 3 postoperative days.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Bleeding

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing cardiac surgery with the history of aspirin and/or ADP receptor antagonist for at least 7 days prior the surgery Exclusion Criteria: * Emergent surgery * Heart transplant surgery * Implantation of ventricular assist devices * Enrollment into conflicting study

Locations (1)

Sheba Medical Center

Tel Litwinsky, Israel

RECRUITING

Outcomes

Primary Outcomes

Re-sternotomy d/t Bleeding

Time frame: Hospitalization Period

Secondary Outcomes

Chest tube output during first 24 hours after the surgery

Time frame: 24 hours

Data from ClinicalTrials.gov

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