Mechanisms of Hypoglycemia Associated Autonomic Dysfunction, Q4-Atomoxetine

Inclusion Criteria: * Healthy individuals aged 18-50 years * Type 1 Diabetes individuals aged 18-50 years * BMI \<40 kg/m2 * Females of childbearing potential with negative urine pregnancy test * Volunteers over 40 years of age, a cardiac stress test with no clinically significant conduction or ischemic changes Exclusion Criteria: The following groups of subjects will be excluded from the study: * Pregnant women * Subjects unable to give voluntary informed consent * Subjects on anticoagulant drugs or with known bleeding diatheses * Subjects with uncontrolled hypertension, heart disease, cerebrovascular incidents * Subjects taking MAOIs * Subjects with narrow angle glaucoma * Subjects with diagnosed psychiatric disorders * Subjects with allergy to atomoxetine, heparin, or lidocaine Physical Exam Exclusion Criteria: * Uncontrolled severe hypertension (i.e., blood pressure greater than 150/95) * Clinically significant Cardiac Abnormalities (e.g. Heart Failure, Arrhythmias, ischemic tachycardia, S-T segment deviations, etc.) from history or from cardiac stress testing in subjects \> 40 years old. * Pneumonia * Hepatic Failure/Jaundice * Renal Failure * Acute Cerebrovascular/ Neurological deficit * Fever greater than 38.0 C Screening Laboratory Tests Exclusion Criteria Blood values as defined in protocol