AKIN Criteria: Acute Kidney Injury After On-Pump Coronary Artery Bypass Graft (CABG)

Hospital de Base817 enrolled

Overview

The purpose of this study is evaluate clinical outcomes and 30-day mortality after on-pump CABG.

Eight hundred and seventeen patients was enrolled in this series and divided into to groups: Group AKI (-) - patients without acute kidney injury after on-pump CABG. Group AKI (+) - patients with acute kidney injury after on-pump CABG. AKI was defined as an absolute increase in serum creatinine (SCr) of more than or equal to 0.3 mg/dl (≥ 26.4 μmol/l) or a percentage increase in SCr of more than or equal to 50% (1.5-fold from baseline). The change in SCr concentration was defined as the difference between immediate postoperative concentration and the highest concentration during the stay in ICU. Clinical Outcomes and 30-day mortality was evaluate in this patients.

Study Type

OBSERVATIONAL

Enrollment

817

Conditions

Kidney Failure

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients underwent on-pump coronary artery bypass grafting * Patients with at least two serum creatinine values within 48 hours. Exclusion Criteria: * Patients with end-stage kidney disease requiring renal replacement therapy.

Outcomes

Primary Outcomes

To test the hypothesis that patients with acute kidney injury after on-pump CABG have higher 30-day mortality

Time frame: 30 days

Secondary Outcomes

To compare clinical outcomes in patients with and without acute kidney injury after on-pump CABG

Time frame: 30 days

Data from ClinicalTrials.gov

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