Neutropenic Fever, Inflammatory Markers and Sepsis in Haematological Patients

Kuopio University Hospital273 enrolled

Overview

The aim of this study is to find out whether inflammation markers including cardiac markers have predictive value in evaluation of pathogenesis of sepsis in neutropenic haematological patients.

Adult AML and ASCT patients with neutropenic fever. Observation of possible progress to severe sepsis or septic shock. Blood sample collection on days 0-3 (from the beginning of neutropenic fever).

Study Type

OBSERVATIONAL

Enrollment

273

Conditions

Sepsis

Interventions

Severe sepsis vs. non-severe sepsisOTHER

To compare these two groups

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * diagnosis: acute myeloid leukaemia * age under 70 years * neutropenic fever Exclusion Criteria: * age above 70 years * no neutropenic fever

Locations (2)

Kuopio University Hospital

Kuopio, Finland

Kuopio University Hospital

Kuopio, Finland

Outcomes

Primary Outcomes

This study evaluates epidemiology, microbiology and outcome of neutropenic fever and severe sepsis in haematological patients with special reference to the kinetics of inflammatory markers.

This study evaluated epidemiology, microbiology and outcome of neutropenic fever and severe sepsis in haematological patients with special reference to the kinetics of specific inflammatory markers.

Time frame: Within neutropenic period after treatment

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.