A prospective, multi-module intervention based on nutrition management, psychosocial support, and a controlled home-based physical exercise training program for patients on LVAD- support will be provided to improve outcomes in terms of survival and patients health-related quality of life (HRQoL) for the long-term. Physical capacity, neurocognitive, psychological factors, and adverse events will be assessed as potential independent indicators for HRQoL.
The multi-module intervention program for patients on LVAD support includes nutrition management, home-based ergometer training program, psychosocial support and neurocognitive screening. The nutrition management and physical reconditioning program will be supplemented by psychosocial support targeting the risk of increased stress, anxiety, and depression level. Moreover, standardized neurocognitive screening procedures will be administered to detect neurocognitive dysfunction (except stroke) and will be assessed for their potential to predict limitations in QoL. Adverse events like re-hospitalizations, thromboembolic and bleeding events will be monitored and assessed for their potential to negatively impact QoL.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
80
The multi-module rehabilitation program includes: 1. Nutrition management 2. Home-based ergometer training program 3. Psychosocial support
Hannover Medical School, Clinic for Cardiac, Thoracic, Transplantation and Vascular Surgery
Hanover, Germany
RECRUITINGHannover Medical School
Hanover, Germany
RECRUITINGIncrease in Quality of Life between hospital discharge after LVAD implant and explantation at least three month
Time frame: between hospital discharge after LVAD implant and explantation at least three month
Anxiety and depression scores
Time frame: between hospital discharge after LVAD implant and explantation at least three month
Maximum exercise capacity
Time frame: between hospital discharge after LVAD implant and explantation at least three month
Body mass index
Time frame: between hospital discharge after LVAD implant and explantation at least three month
Neurologic events
Time frame: between hospital discharge after LVAD implant and explantation at least three month
Adverse events
Time frame: between hospital discharge after LVAD implant and explantation at least three month
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