Comparative Efficacy of Bifonazole Cream vs Placebo After Nail Ablation With Urea Paste

Inclusion Criteria: * Age of at least 18 years; * Positive clinical findings of onychomycosis according to the judgement of the investigator (e.g. thickening, discoloration, structural changes, misshaped nails); * Positive mycological findings (positive microscopy and positive culture with identification of pathogen) in material taken from affected nail sites before the start of treatment; * Nail mycosis with an affected nail area between 20% and 50% in the target nail, * Nail mycosis in not more than 3 nails (each nail not more than 50% infected area) Exclusion Criteria: * Doubtful or negative mycological findings; * Proximal subungual onychomycosis (PSO); * Topical antimycotic treatment of feet or hands within 4 weeks prior to screening, topical treatment of onychomycosis of feet or hands within 12 weeks prior to screening; * Systemic antimycotic treatment within 12 weeks prior to screening; * Failure to treat tinea pedis/manus (diagnosed at screening) successfully with topical treatment between screening visit and visit 1 (baseline); * Tinea pedis/manus at visit 1 (baseline); * Uncontrolled diabetes mellitus * Psoriasis * Peripheral arterial disease * Chronic venous insufficiency; * Diabetic neuropathy; * History of hypersensitivity to bifonazole, or any other similar pharmacological agents or components of the products; * Known sensitivity to plasters.