Evaluation of the Reasons and Consequences of Bleeding in Late Teens and Early Adulthood Patients With Severe Hemophilia A

Inclusion Criteria: * Severe hemophilia A (\<2%) * For subjects who elect staying on Prophylaxis only: Have been on continuous prophylactic treatment for the past 5 years prior to study entry * For subjects who elect switching to on-demand only: Have been on continuous prophylactic treatment for the past 5 years, but may have been on intermediate or reduced prophylaxis for the 1-12 months prior to study entry * For subjects currently on-demand: a retrospective arm of subjects who have been on continuous prophylactic treatment for at least 5 years and switched to on-demand treatment between 13 and 24 months prior to study entry * Current treatment with rFVIII Exclusion Criteria: * Other known hematological / bleeding disorders other than hemophilia A * Participating on another study that may have an impact on bleeding or the objectives of this study * Known alcohol and drug abuse