AZD6765 Single and Multiple Ascending Dose Study in Healthy Male and Female Japanese and Caucasian Subjects

Inclusion Criteria: * Body mass index (BMI): 18 to 27 kg/m 2 * Female subjects must be postmenopausal for at least 1 year, surgically sterile, or using a reliable method of contraception at screening. * Male subjects must be willing to use accepted contraceptive methods, avoid unprotected sex, and donating sperm until 3 months after drug administration. Exclusion Criteria: * Clinically relevant disease and/or abnormalities (past or present) * Clinically relevant abnormalities in physical examinations,vital signs,clinical chemistry, hematology or urinalysis at screening as judged by the investigator * Use of any prescription medication within 14 days of Day 1 * Use of over-the-counter (OTC) medication (with the exception of acetaminophen), vitamin/nutritional supplements and herbal preparations within 14 days of Day 1 * Smoking in excess of 5 cigarettes per day or the equivalent within 28 days of Day 1