* The Study analyses the influence of selected factors on adherence to Betaferon treatment in patients with early multiple sclerosis (MS). The Investigator will document the relevant medical data regarding multiple sclerosis at every hospital visit, the patient will fill in two questionnaires at every visit: one about coping with the disease and the other about anxiety and depression. * The Study particularly looks at the role of the support of the patient given by the multiple sclerosis nurses.The nurse will provide additional standardised information at start of treatment and will regularly phone the patient to ask standardised questions about the general condition with regard to the treatment, the disease and social support. At the end of the Study it will be assessed if the supportive measures and the standards in terms of adherence management in the hospital have some influence to increase long-term treatment adherence.
Study Type
OBSERVATIONAL
Enrollment
1,723
Patients after first clinical events suggestive of MS (according to SMPC) and patients with RRMS within the first two years of diagnosis
Unnamed facility
Many Locations, Argentina
Unnamed facility
Many Locations, Bahrain
Unnamed facility
Many Locations, Belgium
Unnamed facility
Many Locations, Bosnia and Herzegovina
Unnamed facility
Many Locations, Canada
Unnamed facility
Many Locations, China
Unnamed facility
Many Locations, Colombia
Unnamed facility
Many Locations, Czechia
Unnamed facility
Many Locations, Egypt
Unnamed facility
Many Locations, Estonia
...and 26 more locations
Proportion of patients adhering to treatment
Time frame: 6, 12, 18 and 24 months
Rate of early treatment termination
Time frame: 6, 12, 18 and 24 months
Rate of study dropout
Time frame: 6, 12, 18 and 24 months
Predictive value of BL parameters, WCQ, HADS, RODQ
Time frame: 12 and 24 months
WCQ (Ways of Coping Questionnaire)
Time frame: 6, 12, 18 and 24 months
HADS (Hospital Anxiety and Depression Scale)
Time frame: 6, 12, 18 and 24 months
RODQ (Risk of Dropout Questionnaire)
Time frame: Monthly over 6 months; every other month thereafter
EDSS (Expanded Disability Status Scale)
Time frame: 6, 12, 18 and 24 months
Relapse rate
Time frame: 6, 12, 18 and 24 months
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