Medical Polypectomy and Predictors of Response

Inclusion Criteria: * male or female * 18-75 years of age * bilateral nasal polyposis Grade 2 and above * with or without asthma * with or without atopy or aspirin sensitivity * written informed consent Exclusion Criteria: * unilateral nasal polyposis * polypoid lesion suspicious of inverted papilloma, malignancy, Wegeners granulomatosis, sarcoidosis * known or suspected hypersensitivity to fluticasone propionate or any other constituents of the Investigational Medicinal product (IMP). * Any clinically significant medical condition or abnormality, which, in the opinion of the investigator, might compromise the safety of the subject or which might interfere with the study. * significant (≥50%)septal deviation * inability to comply with the requirements of the protocol * females who are pregnant, lactating or planning to become pregnant.