This is a study designed to compare the effects of 2 long-acting insulins, detemir and insulatard, on energy expenditure,weight, fat composition, gut hormone profiles, glycaemic control and fat and muscle gene expression over a 6 month period.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
30
Insulatard insulin used as long-acting insulin for 16-week treatment phase of study.
Detemir insulin used as long-acting insulin in treatment phase of study.
Cedar Centre, Royal Surrey County Hospital
Guildford, Surrey, United Kingdom
Weight change
Time frame: 6 months
Energy Expenditure
Time frame: 6 months
Fat composition
Time frame: 6 months
Fat & muscle gene expression
Time frame: 6 months
Glycaemic control
Time frame: 6 months
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