Mechanisms of Fronto-Subcortical Dysfunction: Comparing PD and OCD

Sheba Medical Center100 enrolled

Overview

The purpose of this study is to characterize and compare irregularities in dopaminergic function in fronto-subcortical circuits, between Parkinson's Disease patients (ON and OFF medication) and patients with obsessive-compulsive disorder, by examining performance on cognitive tasks involving cognitive flexibility, decision-making, and attentional bias.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Parkinson's Disease Obsessive-Compulsive Disorder

Eligibility

Sex: ALLMin age: 16 YearsMax age: 85 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * idiopathic PD or * OCD * for control group - age-matched to study groups Exclusion Criteria: * psychotic symptoms (past or present) * head injury with loss of consciousness * other neurological conditions (excepting PD in PD group) * for OCD group - use of dopaminergic medications

Central Contacts

Sharon Hassin, MD

CONTACT

97235305791 shassin@post.tau.ac.il

Sari Meril, M.Sc

CONTACT

972

Data from ClinicalTrials.gov

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