In this study, we want to compare two different kinds of artificial ventilation to see if one encourages faster weaning from breathing support and if one provides better sleep quality. These artificial ventilation types are: 1. Pressure support ventilation; the standard ventilation that we use for the patients in the Respiratory Acute Care Unit. Pressure support ventilation ventilators use constant air pressure to assist patients with their breathing. 2. Proportional assist ventilation; a newer way of helping people with their breathing. The air pressure provided by proportional assist ventilation ventilators varies with the size of the breath that a person takes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
12
Proportional Assist Ventilation will be used to ventilate the patients.
Pressure Support ventilation will be used to ventilate the patients.
Massachusetts General Hospital
Boston, Massachusetts, United States
Length of time mechanically ventilated in the RACU
Time frame: 30 days
Sleep quality
Time frame: 48 hours
Inflammatory mediator levels
Time frame: 30 days
Hospital mortality
Time frame: 30 days
60 day mortality
Time frame: 60 days
180 day mortality
Time frame: 180 days
365 day mortality
Time frame: 1 year
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