We hypothesize that simvastatin in combination with ICS might have synergistic anti-inflammatory effects on airway inflammation in asthmatic patients
To determine the additive effect of simvastatin on airway inflammation in ICS-treated patients with persistent asthma by measuring eosinophil counts in induced sputum
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
53
10 mg per oral once daily for 8 weeks
1 table per day for 8 weeks
Kittipong Maneechotesuwan
Bangkoknoi, Bangkok, Thailand
Sputum eosinophil
Time frame: 8 WEEKS
FEV1
Time frame: 8 WEEKS
PC20
Time frame: 8 weeks
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