Performance of CAST (Cellular Antigen Stimulation Test) in Patients With Wasp Venom Allergy: Evaluation of Neutralizing IgG Subclasses

University of Zurich

Overview

To determine which subclass of IgG in the serum of patients undergoing SIT against wasp venom is able to neutralize the allergen, and therefore to prevent a positive CAST

Study Type

OBSERVATIONAL

Conditions

Wasp Venom Allergic Patients

Interventions

Taking blood samplesOTHER

No intervention is done. Only blood samples are taken.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion criteria: * male and female patient with allergy to wasp venom grade III and IV according to H.L. Müller * 18-75 years * planned SIT against wasp venom or finished 5 years SIT against wsp venom (10/10) Exclusion criteria: * oral corticosteroids * chromogycin * ketotifen * immunosuppressive drugs within the last 2 years

Locations (1)

Unnamed facility

Zurich, Switzerland

Data from ClinicalTrials.gov

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