The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone turnover, physical fitness and neuromotor performance in patients with subacute stroke.
Brief periods of Whole body vibration (WBV) have been shown to improve bone density in post-menopausal women and children with cerebral palsy. In addition to the apparent benefits on bone health, WBV has been shown to increase muscle strength, postural control, muscular blood flow and oxygen uptake in various populations. Therefore, WBV can potentially be used as a tool to improve muscle strength, balance, and cardiovascular performance, especially for those with relatively low level of functioning. Stroke patients are therefore possible beneficiaries of WBV, as they often demonstrate muscle weakness, balance deficits, and poor cardiovascular function, in addition to bone loss. Only one pilot study has examined the effects of WBV in stroke patients. Van Nes et al.showed that postural stability in chronic stroke patients is improved after a few minutes of WBV at 30Hz and 3mm amplitude. The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone turnover, physical fitness and neuromotor performance in patients with subacute stroke.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
In their regular physiotherapy sessions, the subjects in the experimental group will receive WBV (20-240Hz, 10-minute sessions, 1 session per day, 5 sessions per week). The vibration loading will be carried out using the Fit-Vibe System (Germany), which is a vibration platform that is capable of generating vertical vibration.
The subjects in this group will perform the same exercises on the vibration platform as in the experimental group for the same duration, but no vibration will be given.
Tung Wah Hospital
Hong Kong, Hong Kong
RECRUITINGLevel of bone resorption marker CTx
Time frame: baseline, immediately after treatment, and 2-month follow-up
Level of bone formation marker, BSAP
Time frame: baseline, immediately after treatment, and 2-month follow-up
Six minute walk test
Time frame: baseline, immediately after treatment, and 2-month follow-up
Ankle arm index
Time frame: baseline, immediately after treatment, and 2-month follow-up
Functional Ambulation category
Time frame: baseline, immediately after treatment, and 2-month follow-up
Leg muscle strength (hand-held dynamometry)
Time frame: baseline, immediately after treatment, and 2-month follow-up
Berg Balance Scale
Time frame: baseline, immediately after treatment, and 2-month follow-up
Modified Ashworth Scale of Spasticity
Time frame: baseline, immediately after treatment, and 2-month follow-up
Sensory threshold to light touch in the foot
Time frame: baseline, immediately after treatment, and 2-month follow-up
Fugl-Meyer Motor Assessment
Time frame: baseline, immediately after treatment, and 2-month follow-up
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