Efficacy and Safety of a PN Regimen Containing n-3 Fatty Acid in Patients Considered After GI Surgery

Inclusion Criteria: * Patients considered for major surgery for gastric and colorectal cancer * expected requirement for post operative PN or TPN of at least 7 days * possibility of PN/TPN provision 1 day prior to surgery * Age \>18 years old and \<80 years old * Hemodynamically stable * Written Informed consent Exclusion Criteria: * Participation in a clinical study with an investigational drug or an investigational medical device within one month prior to the start of study * Patients with sepsis, severe sepsis or septic shock * Known or suspected drug abuse * Intrahepatic cholestasis * General contraindications for infusion therapy such as acute pulmonary edema, hyperhydration and decompensated cardiac insufficiency * Pregnancy (positive in urine) or lactation * Autoimmune disease e.g. HIV * Known hypersensitivity to egg-, soy-, and fish proteins or any of the ingredients of the investigational products * Hemodynamic failure of any origin (hemorrhagic shock, myocardial infarction, cardiac failure) * Alterations of coagulation (thrombocytes \<150000 /mm3), PT \< 50%, PTT \> 40 sec * Ketoacidosis caused by Diabetes mellitus within 7 days prior to onset of study * Renal insufficiency with serum creatinine \> 1.4 mg/dL (\>124 µmol/L) * Patients with severe liver dysfunction with bilirubin \>2.5 mg/dL (\> 43 µmol/L) * Lipid disorders, in particular fasting serum triglycerides \> 250 mg/dL (\>2.85 mmol/L),