The primary objective of this study is to investigate the initial antibiotic effects in the treatment of bacterial conjunctivitis symptoms in subjects one year of age and older.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
24
Moxifloxacin 5mg/mL 3 times daily for 7 days
Balanced Saline Solution for 3 doses, then Moxifloxacin 5mg/mL 3 times daily for 7 days
Contact Alcon Call Center For Trial Locations
Fort Worth, Texas, United States
Exploratory Outcomes From Digital Photography
Photographs were taken before and after treatment. Outcome is the number of patients whose photographs showed a subjective visual change based upon an exploratory review of patient photographs in signs of bacterial conjunctivitis before and after treatment.
Time frame: 24 hours after administration of first dose
Exploratory Evaluation of Changes in Ocular Signs and Symptoms
Number of patients who had clinical resolution (0 on all scales below) from baseline (Day 1) to Day 2 in ocular and symptoms of bacterial conjunctivitis: Bulbar Conjunctival Injection - 0 (none) to 4 (Severe) scale. Conjunctival Discharge (Mucopurulent) - 0 (none) to 3 (Severe) scale. Lid Erythema - 0 (none) to 3 (Severe) scale. Lid Swelling - 0 (none) to 3 (Severe) scale. Palpebral Conjunctiva - 0 (none) to 3 (Severe) scale. Foreign Body Sensation - 0 (none) to 3 (Severe) scale. Tearing - 0 (none) to 3 (Severe) scale. Photophobia - 0 (none) to 3 (Severe) scale.
Time frame: Baseline (Day 1) to Day 2
Microbiological Culture Evaluation/Eradication Percent - Enterobacter Faecalis and Candida Albicans
Eradication percent (absence of specified bacteria) of each bacteria identified at Day 1
Time frame: 24 hours after administration of first dose
Microbiological Culture Evaluation/Eradication Percent - Eradication of All Other Isolates and Corynform-like
Eradication percent (absence of specified bacteria) of each bacteria identified at Day 1
Time frame: 24 hour after administration of first dose
Microbiological Culture Evaluation/Eradication Percent - Staphylococcus Aureus, Steptococcus Pneumoniae, and Enterobacter Cloacae
Eradication percent (absence of specified bacteria) of each bacteria identified at Day 1
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Time frame: 24 hours after administration of first dose