A Study of the Effect of Estrogen on Estrogen Receptor Biomarkers in Healthy Postmenopausal Women (0000-094)(COMPLETED)

Inclusion Criteria: * Subject is healthy, postmenopausal woman at least 40 years of age with onset of menopause within 10 years of screening * Subject has a normal mammogram at screening * Subject has had a normal Pap-smear within 3 years of screening. Subjects who have not had a Pap-smear in the last 3 years will have the option to have the test at screening * Subject agrees to avoid medications that cause dry mouth or otherwise affect saliva flow * Subject is willing to avoid strenuous exercise during the study * Subject is willing to avoid use of mouthwash or salt water rinses during the study * Subject is willing to avoid use of teeth whitening products * Subject is willing to avoid eating and/or drinking grapefruit products * Subject is willing to limit alcohol consumption to 2 drinks a day * Subject is willing to limit caffeine consumption to 3 cups of coffee (or equivalent) per day * Subject is a non-smoker Exclusion Criteria: * Subject has a history of multiple and/or severe allergies to drugs or food * Subject has a cold or viral infection within 2 weeks of Visit 2 * Subject is taking antibiotics within 2 weeks of Visit 2 * Subject needs dental work or procedures during the study * Subject has used any estrogen or progesterone preparation or product containing phytoestrogens within 3 months of screening * Subject is unable to discontinue anti-coagulants