The Biomarker and Cardiac Function in Sepsis

Inclusion Criteria: * Sepsis patients with 2 of the followings when arrival ER and treated \> 6 hours: * BT \>38℃ or\<36℃ * HR \>90/min * RR \>20/min or PaCO2 \< 32 mmHg * WBC count \>12×109/L or \<4×109/L or immature form \>10％ Exclusion Criteria: * Age \< 18 * Major trauma patients * Pregnancy * Willing to do not aggressive treatment