CrossBoss and Stingray Catheter and Entera Guidewire Chronic Total Occlusion (CTO) Study

Inclusion Criteria: * Suitable for coronary intervention * de novo or restenotic CTO at least 3 months old, in proximal or mid coronary artery segment, 3.0-5.0 mm in diameter * Mild/moderate proximal vessel tortuosity * Mild/moderate lesion angulation * Mild/moderate calcification * Satisfactory distal vessel visualization * Mild/moderate side branch interference * 19 years old * BMI\<40 * LVEF\>20% * Signed informed consent Exclusion Criteria: * Extensive dissection from guidewire manipulation * SVG or in-stent CTO * Aorto-ostial CTO * Unable to take aspirin, Clopidogrel, or Ticlopidine * Thrombus/vessel filling defects * Severe cerebrovascular disease/stroke within 1 month * Intervention within 2 weeks * Renal insufficiency * GI bleeding * Active infection * Life expectancy \<2 years * Significant anemia * Uncontrolled hypertension * Severe electrolyte imbalance * Anaphylaxis to contrast * NYHA class IV * Unstable angina requiring intervention * MI within 2 weeks * Uncontrolled diabetes * Participating in another protocol * Unwilling/unable to comply with protocol * Angina/ischemia caused by target vessel