This study is a comparison of multifocal electroretinogram assessment between the laser treatment group and the photodynamic therapy group in chronic central serous chorioretinopathy.
1. Laser Group: extrafoveal focal leakage on FAG 2. PDT Group: no definite focal leak on FAG subfoveal or juxtafoveal focal leakage on FAG, or serous retinal pigmentary epithelial detachment involving foveal center Inclusion criteria 1. Chronic serous chorioretinopathy (over 3 months) when subretinal fluid persisted in the subfoveal region demonstrated by clinical examination and OCT 2. Ability to maintain steady fixation for mfERG 3. Presence of abnormal dilated choroidal vasculature in ICGA 4. Symptom duration over 3 months Exclusion criteria 1. previous PDT or laser treatment history 2. evidence of Choriinal neovascularization in FAG 3. other chorioretinal disorders that can cause macular exudation such as age-related macular degeneration, pathologic myopia, angioid streaks, trauma, inflammatory diseases, retinal vasculopathies, and hereditary dystrophies follow-up Visit 1)baseline 2)1month 3)3months 4)6 months each visit: multifocal electroretinogram, visual acuity, optical coference timography should be measured.
Study Type
OBSERVATIONAL
Enrollment
24
Samsung Medical Center
Seoul, Seoul, South Korea
Multifocal Electroretinogram Amplitudes
Amplitude at first annular ring at multifocal electroretinogram RETIscan (Roland Consult, Wiesbaden, Germany) is used for multifocal retinogram. The recording protocol was chosen according to the International Society for Clinical Electro-physiology of Vision (ISCEV) guidelines.
Time frame: baseline, 1 month, 3 months, 6 months
Best Corrected Visual Acuity
Best-corrected visual acuities were obtained with Snellen charts. Snellen's visual acuity was converted logarithm of the minimum angle of resolution (logMAR) for statistical analysis.
Time frame: baseline, 1 month, 3 months, 6 months
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