Longitudinal Pathogen-colonization in Cystic Fibrosis Airways and Ability to Smell

University of Jena180 enrolled

Overview

Aim of the study is to detect the prevalence of chronic rhinosinusitis, pathogen colonization of the lower and upper airways and, in a sub-cohort the sense of smelling in patients with cystic fibrosis.

The sub-study on the sense of smelling in CF has been finalized in the meantime. Results were published in 2012: Smell in cystic fibrosis. Lindig J, Steger C, Beiersdorf N, Michl R, Beck JF, Hummel T, Mainz JG. Eur Arch Otorhinolaryngol. 2013 Mar;270(3):915-21. doi: 10.1007/s00405-012-2124-2. Epub 2012 Aug 14.

Study Type

OBSERVATIONAL

Enrollment

180

Conditions

Cystic Fibrosis With Other Manifestations Sinusitis

Interventions

nasal lavage and sputum collectionOTHER

non-invasive longitudinal assessment of pathogen colonization in both airway levels

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Subject has a confirmed diagnosis of cystic fibrosis

Locations (1)

University of Jena - CF-Center

Jena, Germany

RECRUITING

Outcomes

Primary Outcomes

Dynamics in CF upper and lower airway colonization with pathogens

longitudinal non-invasive sampling of upper and lower airways in CF

Time frame: 10 years

Assessment of ability to smell in CF patients

Time frame: 3 years

Secondary Outcomes

pulmonary function / BMI

Time frame: 10 years

Central Contacts

Jochen Mainz, MD

CONTACT

+49 3641 938425 Jochen.Mainz@med.uni-jena.de

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.