Memantine and Validation of a New Alzheimer's Disease Scale

Inclusion Criteria: * Diagnosis of probable Alzheimer's disease consistent with NINCDS-ADRDA criteria or with DSM IV TR criteria for Dementia of Alzheimer's type. * Signed informed consent prior to the initiation of any study specific procedures. * Sight and hearing (a hearing aid is permitted) are sufficiently good to allow the undertaking of study-related procedures and psychometric tests. Exclusion Criteria: * Evidence of clinically significant and active pulmonary, gastrointestinal, renal, hepatic, endocrine or cardiovascular system disease. * Intake of any medication that is contra-indicated in combination with memantine. * History of severe drug allergy, or hypersensitivity, or patients with known hypersensitivity to ingredients of memantine or lactose. * Known or suspected history of alcoholism or drug abuse within the past 2 years. * Current or previous treatment with memantine or participation in an investigational study with memantine.