Study of the Relationship Between Sleep Quality and Daytime-Nighttime Variations of Blood Pressure and Plasma Glucose Type I

Overview

The primary objectives are to compare the mean levels of the sleep quality parameters of subjects : with a nocturnal fall of the SBP (Systolic blood pressure), DBP (diastolic blood pressure) and MAP (mean arterial pressure) over of egal to 10% (dipping subjects) and of subjects with a nocturnal fall of SBP, DBP and MAP inferior to 10% (non dipper subjects). The secondary objectives are : Establish correlations between: * The quality of sleep parameters * The parameters of BP variations between the diurnal and nocturnal periods and the awake periods of sleep defined in reference to polysomnography. * The glycemia levels on 24h with a glycemic holter. The parameters of the sympathic system activation evaluated in reference to the measure of the baroreflex sensibility during the awake period.

It is a prospective monocentric study after a preliminary period of depistage of the sleep abnormalities by oximetry at home. The patient would be hospitalized for two consecutive days (J0, J1). And the following evaluations will be done: * Nocturnal oxymetric + Epworth questionnaire + clinical questionnaire to detect sleep perturbations at home. * Blood pressure + heart rate measure * Ambulatory blood pressure monitoring on 24 hours * Polysomnographic measurements during the J0-J1 night spend at the hospital. * Questionnaire of sleep quality and of quality of life. * Glycemic measurements on 24h (J0-J1). * Measure of the baroreflex sensibility during the awake period at J1. * Electrocardiogram * Biological examinations (blood and urinary).

Conditions