Effect of Desmopressin on the Nocturnal Micturition Frequency in Patients With Parkinson Disease

Inclusion Criteria: * Male patients with idiopathic Parkinson Syndrome * 18 to 85 years * Nocturnal Pollakisuria \> 2 mictions /night (documented in Screening phase ) * Na+ i.S \> 135 mmol/l * Patient is able to understand all aspects and individual consequences of the clinical trial * An informed consent signed and dated by the patient is available prior to any study specific treatment * The study is consistent with the patients´ request for an appropriate treatment Exclusion Criteria: * Intake of the following concomitant medication: Carbamazepin, Oxcarbazepine, diuretics (Furosemide, Torasemide), non steroidal antiphlogistics, Loperamide, antidiuretic hormone analoga (besides study medication), drugs for treatment of bladder disfunction, in particular anticholinergics * Central Diabetes insipidus * Known heart insufficiency (NYHA Stad. III und IV) * clinical relevant kidney insufficiency * Habitual and psychogenic Polydipsia * Hypersensitivity or allergy against the trial medication or any other ingredient of the trial medication * Participation in another clinical trial during or within 6 months prior to this clinical trial * Medical or psychological condition, which might endanger the proper conduction of the clinical trial * Known drug or alcohol abuse