Caloric Restriction and Body Weight in Adults

Vanderbilt University79 enrolled

Overview

The purpose of this study is to determine the role of 1. dietary calcium in fecal fat loss and the association between lactose maldigestion, dietary calcium level and source, and weight loss induced by caloric restriction. 2. caloric restriction on biomarkers of inflammation and oxidative stress

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Overweight

Interventions

Dietary calciumDIETARY_SUPPLEMENT

Dairy and non-dairy calcium provided as a part of diet in the amounts of 500 mg/day and 1500 mg/day. Diet contained 70% of daily caloric requirements.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 18 -65 years old * Healthy Exclusion Criteria: * Body weight more than 300 lbs (body composition measurement instrument limit) diabetes * Heart disease

Outcomes

Primary Outcomes

Fat in stool as a percentage of fat intake

Time frame: 3 months of diet

Secondary Outcomes

Weight change

Time frame: 3 months of diet

Data from ClinicalTrials.gov

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