Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia. The study objectives were to assess the potential cardiovascular benefits of reducing personal particulate air pollution exposure by wearing a facemask in healthy volunteers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
15
Subjects to wear a simple face mask for 24 hours prior to the study day and the 24 hours of the study day. They will be instructed to wear the mask as much as possible when indoors and at all times when outdoors.
Subjects will not wear a face mask to reduce their personal exposure to air pollution
Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Medical Union College
Beijing, China
Ambulatory blood pressure
Time frame: During 24 hour study period
Heart rate
Time frame: During 24 hour study period
Heart rate variability
Time frame: During 24 hour study period
Personal air pollution exposure
Time frame: During 2 hour city centre walk
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.