Lawrence Latino Diabetes Prevention Project

University of Massachusetts, Worcester312 enrolled

Overview

The Lawrence Latino Diabetes Prevention Project (LLDPP) is a community-based translational research study which aims to reduce the risk of diabetes among Latinos who have a \>30% probability of developing diabetes in the next 7.5 years per a predictive equation. The project was conducted in Lawrence, Massachusetts; a predominantly Caribbean-origin urban Latino community. Individuals were identified primarily from a community health center's patient panel, screened for study eligibility, randomized to either a usual care or a lifestyle intervention condition, and followed for one year.

The group format of the intervention included 13 group sessions complemented by 3 individual home contacts over one year and was implemented by individuals from the community with training and supervision by a clinical research nutritionist and a behavioral psychologist. Study measures included demographics, Stern predictive equation components (age, gender, ethnicity, fasting glucose, systolic blood pressure, HDL-cholesterol, body mass index, and family history of diabetes), glycosylated hemoglobin, dietary intake, physical activity, depressive symptoms, social support, and quality of life. Body weight was measured at baseline, 6-months, and one-year; all other measures were assessed at baseline and one-year. All surveys were orally administered in Spanish.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

312

Conditions

Metabolic Syndrome

Interventions

lifestyle interventionBEHAVIORAL

A group-based intervention including 13 group sessions complemented by three individual home visits was developed using principles of social learning theory and patient-centered counseling. The intervention was intended to increase awareness of diabetes prevention strategies, foster positive diabetes prevention attitudes (i.e., self-efficacy) and promote healthy lifestyle behaviors in the target Latino population using literacy-sensitive and culturally-tailored strategies and materials.

Eligibility

Sex: ALLMin age: 25 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Is Latino/Hispanic; * Has a 7.5 year likelihood of becoming diabetic of greater than or equal to 30% as predicted by the Stern formula; * Is greater than or equal to 25 years of age; * Has a BMI greater than or equal to 24 kg m2. Exclusion Criteria: * An inability or unwillingness to give informed consent; * Has clinically diagnosed diabetes, or a fasting blood sugar of greater than or equal to 126 mg/dl; * Plans to move out of the area within the study period; * Has a psychiatric illness which limits ability to participate; * Has no telephone; * Is unable to walk unaided, or cannot walk five city blocks (1/4 mile) without stopping; * Is not cleared for the PA component by the pt's GLFHC primary care provider; * Has a medical conditions likely to limit lifespan; * Is on medications or has a medical condition that interfere with the assessment for diabetes.

Locations (1)

Lawrence Senior Center

Lawrence, Massachusetts, United States

Outcomes

Primary Outcomes

Weight loss.

Time frame: 1 year

HgbA1c

Time frame: 1 year

Secondary Outcomes

Change in fasting blood sugar.

Time frame: 1 year

Changes in LDL- and HDL-cholesterol.

Time frame: 1 year

Change in blood pressure.

Time frame: 1 year

Change in depression.

Time frame: 1 year

Change in quality of life.

Time frame: 1 year

Data from ClinicalTrials.gov

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