This study is testing the effects of exercise and dietary change on weight reduction and biological markers associated with breast cancer risk in breast cancer survivors of Hispanic or African descent (n=45). This is a randomized, crossover pilot and feasibility study to test the effects of a 30-minute circuit-based exercise program that combines resistance training with aerobic exercise in conjunction with a low-fat calorie reduced diet. Participants will be randomized to either an immediate 6-months of exercise and dietary change, or a delayed group who will begin their exercise and dietary change program 6-months after the study begins. Participants in the immediate group will be followed for an additional 6-months in order to evaluate adherence to the exercise and dietary change recommendations. Participants in both groups will exercise at a neighborhood Curves® facility at least 5 times per week for six months and will participate in a series of nutrition education classes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
42
6 months of combined resistance training and aerobic exercise (5 times per week x 30 minutes) plus 6-week nutrition counseling class
Columbia University
New York, New York, United States
Change in weight
Time frame: 6 months, 12 months
Intervention adherence
Time frame: 6 months, 12 months
Barriers to participation
Time frame: 3 months, 6 months, 9 months, 12 months
Predictors of adherence
Time frame: 3 months, 6 months, 9 months, 12 months
Changes in anthropometric measures
Time frame: 3 months, 6 months, 9 months, 12 months
Changes in fitness
Time frame: 3 months, 6 months, 9 months, 12 months
Changes in hormonal biomarkers
Time frame: 3 months, 6 months, 9 months, 12 months
Changes in metabolic markers
Time frame: 3 months, 6 months, 9 months, 12 months
Changes in psychological and quality of life measures
Time frame: 3 months, 6 months, 9 months, 12 months
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