Evaluation of Nephrogenic Systemic Fibrosis (NSF) in Patients With Chronic Kidney Disease Following OptiMARK Injection

Inclusion Criteria: * Referred for contrast-enhanced MRI using gadoversetamide; * Have a documented estimated glomerular filtration rate (eGFR) of \<60 mL/min/1.73 m2 within the past 6 months or ESRD requiring dialysis; and * Willing and able to provide written consent (themselves or by a legally authorized representative) and agree to abide by study requirements, including being seen by a dermatologist and undergoing a skin biopsy if NSF is suspected. Exclusion Criteria: * Have experienced a previous hypersensitivity reaction to a GBCA; * Have pre-existing NSF or NSF-like symptoms; or * Have been exposed to a GBCA within 12 months prior to the index procedure; or * Has a medical condition or other personal situation that would prevent providing follow-up information, completing clinic visits or otherwise supplying meaningful data to meet study objectives.