Glycosaminoglycans During Septic Shock - a Temporal Study

Region Skane

Overview

We have previously shown that the plasma level of glycosaminoglycans (GAG) in septic shock patients are elevated compared to controls. The purpose of this study is to investigate the temporal dynamic of the blood level of GAG in ten septic shock patients. In addition, to assess the kinetics of GAG during septic shock we examine the liver function by galactose elimination capacity as well as excreted urinary GAG.

Study Type

OBSERVATIONAL

Conditions

Septic Shock

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 2 out of 4 SIRS criteria, where the circulatory criteria must be fulfilled * Clinical sepsis is suspected * Informed consent from relative * Study subject must be over 18 years old Exclusion Criteria: * Pregnancy * \>24h post sepsis diagnosis * Ongoing oral or intravenous cortisone treatment for more than one month. * Malignancy with metastasis

Locations (1)

Intensive Care Unit, Lund University Hospital

Lund, Sweden

Data from ClinicalTrials.gov

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