Topical 5-ALA-PDT With Blu-U Therapy Versus Topical 5-ALA With Pulse Dye Laser In Treating Recalcitrant Acne Vulgaris

Inclusion Criteria: * 18-79 years of age * Patients who failed the topical and oral antibiotics after 6 month therapy. * Patients who failed the topical retinoids after 6 month therapy. * Patients that are not good candidate to start oral isotretinoin (Accutane) due to contraindications. Exclusion Criteria: * Patients who have had Isotretinoin therapy less that 1 year prior to this ALA-PDT procedure. * Patients who have an adverse reaction to light exposure (for example photo- exacerbated seizures). * Patients with a history of porphyria.