Nasal Provocation Test With Lysine-Acetylsalicylate (ASA) in Patients With Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Hypersensitivity

Inclusion Criteria: * Patients with history of ASA/NSAIDs hypersensitivity with mucocutaneous symptoms and/or respiratory symptoms Exclusion Criteria: * Patients who cannot discontinue drugs before the test as follow * Nasal corticosteroids/Oral corticosteroids/Leukotriene modifiers for 1 week * Short-acting antihistamines for 3 days * Nasal a-mimetics/Oral a-mimetics/Local cromones for 24 hours * Contraindicated for nasal provocation test: pregnant, exacerbation of allergic rhinitis/asthma, having upper respiratory tract infection within 2 weeks prior to the test, having nose surgery within 8 weeks prior to the test, having severe systemic disease(s) * Having factors interfere nasal provocation test with Lysine-ASA such as massive nasal polyp, nasal septal perforation, total nasal obstruction at least 1 nostril