This clinical study is designed to evaluate the safety of oral administration of the medical food Hoodia to patients with non alcoholic fatty liver disease. Oral administration of Hoodia is common in many western world countries for appetite suppression and as a food supplement or medical food used for dietary purposes. Nonalcoholic steatohepatitis or NASH is a common, often "silent" liver disease which affects about 2%-5% of Americans. NASH is strongly associated with the metabolic syndrome, diabetes type-2 and obesity and can lead to cirrhosis, HCC, liver transplantation or death.This clinical trial has been designed to assess the safety of short term oral administration of Hoodia to patients with NASH.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
20
PO administration of 1 Tab Hoodia gordoni extract per day.
PO Placebo pill
Hadassah Medical Center
Jerusalem, Israel
decreased insulin resistance
Time frame: 30 days
safety
Time frame: 60 days
reduced hepatic injury
Time frame: 30 days
reduced weight/BMI/abdominal circumference
Time frame: 30 days
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