Application and Generalization of Flutter Mucus Clearance Device

Inclusion Criteria: * Pulmonary department: available to perform the device, in-hospital patients * Male and female * Age: 45 - 85 years * Chronic bronchitis, COPD * Thoracic surgery department and surgical department (upper abdomen): * Patients with endotracheal intubation of general anesthesia * Age: 40-75 years Exclusion Criteria: * Not available to perform the procedure * Untreated pneumothorax * Diffusion interstitial lung disease * Acute coronary syndrome * Third stage hypertension * Advanced cancer * Severe heart, liver, renal , blood system and endocrine system dysfunction * Noninvasive mechanical ventilation more than 6 hrs per day * Patients with invasive ventilation and cannot weaning and extubation within 48 hours * Active hemoptysis