The Purpose of this study is to predict antidepressant response in advance using pharmacogenomics and peripheral biological markers in depressed patients.
The difficulties to treat depressed patients are 1)the patients don't respond to antidepressant is about 40% of which, and 2) The time lag is existed until the patients respond to antidepressant and show the treatment effects. If it is predicted the response of antidepressant in advance, it would be overcome such problems. Drug response generally is known to be related to the individual genetic information and the environmental factors. We are going to investigation about antidepressant response using these approaches.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
1,000
Antidepressant administration of SSRI class for 6 weeks under therapeutic dose
Antidepressant administration of non-SSRI class for 6 weeks under therapeutic dose
Samsung Medical Center
Kangnam, Seoul, South Korea
RECRUITINGall pharmacogenetic and biological marker variables cause drug response
Time frame: 24weeks
all clinical cause drug response
Time frame: 24weeks
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