Effect of Helicobacter Pylori Treatment on Idiopathic Central Serous Chorioretinopathy (ICSCR)

Tabriz University50 enrolled

Overview

Etiology of ICSCR is not known however recent studies regard the role of immunologic and infectious processes in the pathogenesis of ICSCR.one of these hypothesis is the role of helicobacter pylori in the pathogenesis of ICSCR so perhaps treatment of h pylori have positive effect on the remission of ICSCR.

we will choose 50 cases of patients with ICSCR who are infected with h.pylori.25 cases will receive anti h.pylori regiment and 25 cases as controls will receive no medication.then we will compare the time of submacular fluid resorption and macular thickness and visual acuity among these two groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Central Serous Chorioretinopathy

Interventions

omeprazole, Amoxicillin, metronidazoleDRUG

we will evaluate the effect of medication(anti h.pylori) on the remission of ICSCR

Eligibility

Sex: ALLMin age: 28 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * the persons who are infected with helicobacter pylori and have ICSCR Exclusion Criteria: * history of previous eye surgery ,to have indication of laser therapy,corticosteroid therapy,pregnancy,

Locations (1)

Alireza JavadzadehTabriz

Tabriz, Iran

Outcomes

Primary Outcomes

Subretinal fluid level

Secondary Outcomes

time of sub macular fluid absorption

Data from ClinicalTrials.gov

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