To evaluate the bioavailability of a tablet of AZD1656.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
11
Research site
San Antonio, Texas, United States
Pharmacokinetic variables ( Area under the plasma concentration vs. time curve (AUC), maximum plasma concentration (Cmax), time to reach maximum plasma concentration (tmax), terminal elimination half-life (t½) and apparent oral clearance (CL/F)
Time frame: Blood samples taken up to 72 hours
Pharmacodynamic variables (Plasma glucose)
Time frame: Taken repeatedly during treatment periods
Safety Variables (AEs, BP, pulse, electrocardiogram (ECG), hypoglycaemic symptoms and laboratory variables)
Time frame: Taken during treatment periods
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