This study will determine if Angongniuhuang Pill (Composed of Niuhuang, Yujin, Xijiao, Huangqin, Huanglian, Xionghuang, Zhizi, Zhusha, Bingpian, Shexiang, and Zhenzhu) will have a better effect in restoring consciousness for patients who have suffered from an acute ischemic stroke. The study is designed to look at both consciousness level and overall recovery and recovery of motor function, for example muscle strength and coordination.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
60
7 days of Angongniuhuang Pill
7 days of placebo
Zhongshan Hospital of Fudan University
Shanghai, Shanghai Municipality, China
Glasgow Coma Scale (GCS) within 90 days after stroke onset.
Time frame: 90 days
The percentage of patients of different consciousness level stratified according to the GCS, and the time spent of patients who recovered from coma.
Time frame: 90 days
Global disability on modified Rankin scale at 90 days.
Time frame: 90 days
NIH stroke scale
Time frame: 90 days
Changes in laboratory indexes as safety assessment, including red blood cell(RBC), white blood cell(WBC), platelet(PLT), alanine transarninase(ALT), aspartate transarninase (AST), blood urea nitrogen (BUN), creatinine(Cr) in blood samples; protein, red b
Time frame: 14 days
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