Aspirin Responsiveness in Women at Risk for Cardiac Events

Inclusion Criteria: * Women at least 19 years old * Taking 81 mg aspirin daily, non-enteric coated, for at least one month for the primary prevention of cardiovascular disease. * Able and willing to provide informed consent Exclusion Criteria: * Pregnancy or breastfeeding * Known CHD * Currently taking clopidogrel or ticlopidine * Use of heparin, warfarin, or glycoprotein IIb/IIIa inhibitors within previous 96 hours * Allergy or hypersensitivity to salicylates * Use of other OTC or prescription analgesics or anti-inflammatory medication in the past two weeks * Currently participating in another investigational drug or device study