The purpose of this study is to determine whether a monotherapy with a Beta-Lactam is not inferior to an association of a Beta-Lactam and a macrolide in treating adult patients with community-acquired pneumonia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
601
1.2 g 4x/d OR 1.5 g 3x/d IV
1.2 g 4x/d OR 1.5 g 3x/d IV AND 0.5 g 2x/d IV/PO
HFR-Fribourg, Hôpital Cantonal
Fribourg, Canton of Fribourg, Switzerland
Stadtspital Triemli
Zurich, Canton of Zurich, Switzerland
Centre Hospitalier du Centre du Valais
Sion, Valais, Switzerland
Hôpitaux Universitaires de Genève
Geneva, Switzerland
Time to Clinical Stability (hours)
Time frame: 30 days
All cause mortality
Time frame: in-hospital, at 30 and at 90 days
length of stay
Time frame: 30 days
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Hôpital Neuchâtelois - La Chaux-de-Fonds
La Chaux-de-Fonds, Switzerland
Centre Hospitalier Universitaire Vaudois
Lausanne, Switzerland