Differential Effects of Milk Proteins on Postprandial Lipemia in Response to a Fat-Rich Meal in Type 2 Diabetes

N/ACompletedNCT00819975

Aarhus University Hospital12 enrolled

Overview

Enhanced and prolonged postprandial triglyceride responses involve increased cardiovascular risk in type 2 diabetes. It has been demonstrated that dietary fat and carbohydrates profoundly influence postprandial hypertriglyceridemia in type 2 diabetes, whereas little information exists about the effect of proteins. The purpose of this study is to compare the effects of the milk proteins casein, Whey Isolate, Whey Hydrolysate, and Alphalact-Albumin on postprandial lipid and incretin responses to a high-fat meal in type 2 diabetes.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Postprandial Lipemia Type 2 Diabetes

Interventions

Whey IsolateDIETARY_SUPPLEMENT

Whey HydrolysateDIETARY_SUPPLEMENT

Alphalact-AlbuminDIETARY_SUPPLEMENT

Eligibility

Sex: ALLMin age: 40 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Type 2 Diabetes Exclusion Criteria: * Liver-, Kidney- and/or Heart Disease * Serious Hypertension (160/110 mmHg)

Locations (1)

Department of Clinical Nutrition

Aarhus, Denmark

Outcomes

Primary Outcomes

Triglyceride levels

Time frame: 0h- 2h- 4h- 6h- 7h- 8h postprandial

Secondary Outcomes

Incretin levels

Time frame: 0h- 0.5h- 1h- 2h- 4h- 6h- 8h postprandial

Data from ClinicalTrials.gov

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