ADX10059 Migraine Prevention Study

Inclusion Criteria: * Male and female patients aged 18 to 65 years * History of migraine * Aged ≤ 50 years at onset of migraine history Exclusion Criteria: * Cluster headache or chronic migraine headaches * Currently uses, or within 3 months of Screening, has used: sodium valproate or topiramate and any other drugs used specifically for migraine prophylaxis, for example beta-blockers, calcium channel blockers, tricyclic antidepressants, selective serotonin reuptake inhibitors * Unable to distinguish migraine headache from tension and other types of headache * Current history of psychiatric disorder requiring regular medication * Known history of alcohol abuse * Known clinically significant allergy or known hypersensitivity to drugs * History of a significant medical condition that may affect the safety of the patient or preclude adequate participation in the study * Pregnant or breast-feeding